PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
PDRN Micro Infusion Treatment
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Smooths fine lines & wrinkles

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Brings back youthful radiance

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Boost elasticity & firmness

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Safe and painless to use at home

Excellent 4.8 | 1,465 Reviews

PDRN Advanced Infusion Treatment

$99.90

SAVE 30%

Visibly smooth fine lines, lift sagging skin, and restore youthful firmness in just 5 minutes, twice a month.

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Delivers PDRN deep for collagen production

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Gentle & safe for sensitive skin

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Clinic-level results, zero downtime

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See the difference after your first treatment

  • Deep hydration for a radiant glow
  • Visibly smooths fine lines & wrinkles
  • Boosts skin repair
  • Guaranteed results or your money back

🚨 Last Chance: Secure Your Spot Before This Batch Sells Out

Previous batch sold out in 72 hours and the next one ships tomorrow (Sept 11th).

Order now to get the next available items. Next Batch Ships:

Pre-Order Batches
August 20th SOLD OUT
September 11th 97% SOLD
September 30th 0% sold
Ships by: ...
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EXTENDED CHRISTMAS SALE SALE ENDS IN:

Safe • Painless • Gentle for sensitive skin

Risk-Free 90-Day Guarantee

That's how confident we are in your results. But if you're not thrilled, send it back and we'll refund your purchase.

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Fragrance-Free

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Alcohol-Free

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No Artificial Colorants

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Dermatologically Tested

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Non-Comedogenic

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Cruelty-Free

Real Derm Customer

Transformations

Derm is rated “Excellent” based on 1,400+ reviews

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Wrinkles & Elasticity

Susan A., 70

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Verified Customer

  • Smooths wrinkles & fine lines
  • Restores skin elasticity & firmness
  • Deeply hydrates & plumps
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Sagging Skin & Neck Wrinkles

Regan R., 60

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Verified Customer

  • Firms & lifts sagging skin
  • Reduces neck wrinkles
  • Neck & jaw appear more youthful, firmer and smoother
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Fine Lines & Skin Firmness

Barbara D., 62

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Verified Customer

  • Reduces smile lines & smoker lines
  • Supports the skin barrier for firmer skin
  • Boosts collagen for smoother texture
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Hydration & Youthful Glow

Melanie G., 52

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Verified Customer

  • Visibly smooths fine lines
  • Hydrates & plumps for a youthful look
  • Brightens & refreshes tired skin

Derm's PDRN Micro-Infusion Goes Where Your Anti-Aging Products Can't

Our patented 24K Gold Micro-Infusion Stamp creates microscopic channels, allowing our potent PDRN (Salmon DNA) serum to reach the deeper layers where wrinkles form and skin firmness is lost.

Inside, this regenerative formula stimulates fibroblast activity and cell renewal — boosting collagen and elastin production to smooth fine lines, lift sagging skin, and restore youthful elasticity from within, all without pain, trauma, or a clinic visit.

94%

saw visible improvement in the appearance of fine lines & wrinkles

91%

noticed visibly firmer, more lifted skin after few treatments

96%

said their skin felt healthier, more hydrated, and rejuvenated

The Innovative Formula That Sets Us Apart

HERO INGREDIENT

PDRN (Salmon DNA)

A skin-regenerating molecule that stimulates collagen and elastin production, helping to smooth fine lines, lift sagging skin, and restore youthful firmness from within.

Niacinamide

A multitasking vitamin that brightens uneven tone, refines texture, and strengthens the skin barrier for a healthier, more radiant complexion.

Panthenol (Pro-Vitamin B5)

A soothing active that calms, nourishes, and helps skin maintain softness and resilience — ideal for mature or sensitive skin.

Hyaluronic acid

A powerful hydrator that plumps skin with moisture, softens the look of wrinkles, and supports elasticity and bounce.

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FORMULATED WITHOUT: Artificial colorants, fragrance, alcohol, or comedogenic ingredients. Cruelty free.

VIEW FULL INGREDIENTS LIST.

Water, Glycerin, Butylene Glycol, Trehalose, Panthenol, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Cyclodextrin, Sodium DNA (Salmon DNA), Carbomer, Gentiana Scabra Root Extract, Sodium Hyaluronate, Arginine, Centella Asiatica Extract, Gardenia Florida Flower Extract, Phellodendron Amurense Bark Extract, Caprylyl Glycol, Mannitol, Madecassoside, Centella Asiatica Leaf Extract, Adenium Obesum Leaf Cell Extract, Asiaticoside, Soluble Collagen.

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4 Simple Steps to Firmer, Smoother, Younger-Looking Skin

Just 5 minutes every 2 weeks.

Every order comes with a step-by-step video guide and instructions.

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Prep Your Skin

Cleanse your face and pat dry. Make sure your skin is clean and ready to absorb.

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Attach & Prime

Twist the serum vial directly onto the microneedle head. Hold the device upside down for ~2 minutes to allow full serum flow into the needles.

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Stamp & Infuse

Gently press the device onto your skin, starting from the center of the face and moving outward with 50% overlap. Focus 2–3 passes over areas prone to fine lines, wrinkles, or loss of firmness.

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Let It Absorb

Pat any leftover serum onto the skin and leave it on overnight. Avoid makeup or sun exposure for 24 hours.

One Device, Full-Face Transformation

We’ve combined two advanced technologies to deliver a complete, at-home solution for fine lines, wrinkles, and loss of firmness.

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All so that you achieve

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Smoother, more youthful skin texture

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Visibly firmer, lifted skin

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Clinic-like results from home

Derm vs. Other Solutions.

See The Difference.

Feel The Results.

Traditional shoes

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Aggressive
Clinical Treats

Invasive
Clinical Treats

Basic At-Home Microneedling

Basic At-Home Micro-
needling

Topical 
Creams/Serums

Topical Scar Creams

Targets Fine Lines, Wrinkles & Loss of Firmness at the Source

Clinic-Level Results from Home

No Pain or Extreme Discomfort

Zero Downtime (No Hiding)

No Risk of Skin Damage

Long-Lasting, Genuine Skin Regeneration 

Safe for Mature & Sensitive Skin

Affordable Professional-Grade Solution 

Traditional shoes

5 Reasons You’ll Love This Skin-Rejuvenating System

Without the Pain or the Price Tag

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True Skin Rejuvenation

Our system delivers PDRN deep into the skin’s renewal layers, boosting collagen and elastin where fine lines and sagging begin.

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No Clinic. No Downtime.

Skip invasive procedures and recovery time. Enjoy a 5-minute at-home ritual with real results and zero life on hold.

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Lasting Results. No Illusion.

Tired of temporary fixes? Our system triggers true collagen renewal for improvements that last.

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Gentle on Sensitive Skin

Soothes as it works, supports your skin barrier, and hydrates deeply, without irritation. Designed for even the most delicate skin.

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Smart Investment. Real Payoff.

Why spend thousands at the clinic? Get professional-grade rejuvenation for a fraction of the cost. Your confidence is worth it.

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See Results In 90 Days Or Your Money Back

We believe you’ll love the transformation and we’re willing to prove it.

That’s why this time, we’re making it simple:
Try our PDRN Micro-infusion System for 90 days and if you don’t see visible results, we’ll give you a full refund.

No questions asked.

Get Better Skin Today

90-Day Money Back

Free Express Shipping

Real Skin. Real Change.

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VISIBLE IMPROVEMENT

Redness & Rosacea

I’ve struggled with mild rosacea for years, and most anti-aging products only made it worse. After just a few treatments, the redness is noticeably reduced, and the fine lines around my eyes and mouth are much softer."

Traci G.

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Verified Customer

- from United States

Purchased: 6 Month Supply

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VISIBLE IMPROVEMENT

Smoothed Fine Lines

“I started noticing fine lines in my late 30s, and nothing I tried made a real difference. After four treatments, those lines are so much softer and my skin looks smoother, brighter, and more refreshed. Even my friends have commented that I look more rested!"

Theresa R.

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Verified Customer

- from United States

Purchased: 3 Month Supply

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VISIBLE IMPROVEMENT

More Even Tone

“I used to have uneven skin with dullness that no makeup could fully cover. After some treatments, my complexion looks brighter, smoother, and so much more even. The discoloration have faded, and my skin just looks healthier overall. I feel confident without foundation for the first time in years!”

Lucille B.

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Verified Customer

- from United States

Purchased: 6 Month Supply

Professional Results Without the Professional Price

Feeling good in your skin shouldn’t cost thousands

You could spend each year:

$3,000+

on injectables

$1,800+

on repeat medi-spa visits

$1,100+

traditional skincare

Or, get 6 full treatments and start seeing change from home — for a fraction of the cost of a single clinic session.

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Still Got Questions?

Read Real Reviews From
Our Customers

Customer Reviews
4.8
★★★★★
Based on 1.465 reviews
★★★★★
1147
★★★★☆
271
★★★☆☆
28
★★☆☆☆
6
★☆☆☆☆
13
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Linda

Verified Buyer

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United States

Fine lines are softer finally

I’ve been trying to get ahead of the lines forming around my eyes and mouth for a while. Most things either do nothing or just irritate my skin. This is the first treatment that actually made a visible difference. The fine lines look softer, especially when I smile, and my skin feels a little firmer overall. I’m honestly impressed.

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Samantha

Verified Buyer

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United States

Feels like my skin is holding itself up better

I started noticing a bit of sagging around my jaw (I'm 56). Didn’t want to jump into fillers yet, so I gave this a shot. It’s been two months and my face just looks… lifted? Not in a dramatic way just firmer, healthier and more "together." It’s a good feeling

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Sylvia

Verified Buyer

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United States

THE REAL AMAZING PRODUCT

I have tried every product out there, and this is the one that works after spending thousands of dollars on products that promised results and did nothing. I recently went for my yearly body scan, and my dermatologist said You look amazing. What are you doing? I told her about micro infusion and Derm skin care, the pdrn serum! Well, you now have a new client. Can't say enough about this product:)

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Mary

Verified Buyer

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United States

Love!

I just love this pdrn infusion serum...it's amazing. My wrinkles are alot less noticeable(marionette lines).

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Susanne

Verified Buyer

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United States

Worth the wait

I didn’t notice much until the 2th treatment. Then suddenly… my skin just looked smoother and more lifted. The lines around my mouth were softer, and my overall tone looked brighter. It’s not an overnight miracle, but if you stick with it, it really delivers.

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Kristin

Verified Buyer

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United States

Didn’t realize how dry I was until this

I thought my routine was solid, but apparently I was just layering product on top of thirsty skin. This made everything absorb better and honestly changed how my face feels. It’s softer, less tight, and my forehead lines don’t crease as much during the day...

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Jack

Verified Buyer

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United States

Love it so far

I’m not into skincare. I hate long routines. But this is quick, painless, and after each treatment my skin just feels better. Like it's doing something under the surface. Less oily, more balanced. Even my barber asked what I’m using. That never happens.

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Karen

Verified Buyer

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United States

Skin finally looks awake again

I wasn’t dealing with scars or anything like that, I just felt like my skin looked… tired. Like it lost its glow completely. I wasn’t expecting much, but after a few treatments, something changed. It’s hard to explain, it just looks more alive now and fresher. People have commented on it too, which never happens.

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Sophia

Verified Buyer

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United States

Noticeable change

Used the kit 3 times so far and my skin already feels smoother. The little lines by my eyes aren’t as bad. not a total change yet but better than I expected this quick.

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Sharon

Verified Buyer

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United States

Skin feels better

Week 4 and my skin feels more even and soft. the lines around my mouth look lighter, cheeks maybe a bit firmer too. excited to keep going.

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Emily

Verified Buyer

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United States

Worth sticking with

Not instant but after about 3 weeks I can see smoother texture and my skin looks brighter. jawline even feels a bit tighter. hoping it keeps improving.

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Vanessa

Verified Buyer

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United States

Gentle and easy

Tried other tools that made my skin red for days but this one’s gentle. I only used it twice and forehead lines look softer already. Took me a minute to figure the pressure tho.

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Dorothea

Verified Buyer

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United States

Less wrinkles

Absolutely love this product, I can see my skin plump as I put it on! Definitely seeing less wrinkles! Highly recommend!!

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David

Verified Buyer

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United States

Love it! Noticed a difference in a couple of

Love it! Noticed a difference in a couple of weeks. The how to use video was really helpful for me

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Jane

Verified Buyer

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United States

Hoping to see results soon

Started using the kit about 2 weeks ago. It feels nice after each treatment and the process is easy enough. Haven’t noticed much change in my sagging yet, but I’ll keep at it and stay consistent.

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Vanessa

Verified Buyer

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United States

No big difference yet

Used it 3 times. I like the way my skin feels after, but my wrinkles still look the same to me. Maybe I need more time, idk. Hoping for some visible change soon.

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Heather

Verified Buyer

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United States

Not bad, not amazing either

The product feels high quality and I love that it's more hygienic than rollers. But honestly I haven't seen the kind of results I was expecting. Might be too early. Will update after 2 months.

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Diego

Verified Buyer

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United States

Slight redness after use

I followed the instructions, but my skin feels red and dry for a day after using it. Maybe it’s part of the healing? Not sure if I’m doing something wrong

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Monica

Verified Buyer

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United States

Mixed feelings

I wanted to love this. It’s painless and I like the minimal routine. But I expected faster results after reading the reviews. Maybe my fine lines are just more stubborn than I thought.

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Laura

Verified Buyer

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United States

It’s fine so far

I don’t dislike the product, but it hasn’t blown me away either. No irritation, which is a plus. But waiting to see visible changes.

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Sarah

Verified Buyer

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United States

Improved a little bit

I felt my skin texture has improved.

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Brian

Verified Buyer

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United States

I'm hopeful

I didn’t see any difference in my wrinkles.I thought to use one more and see

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Brittany

Verified Buyer

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United States

It’s too early to tell

I haven't noticed much improvement yet. I've only used it twice since I purchased and received it. I'm looking forward to seeing a greater improvement in the coming weeks.

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Felicia

Verified Buyer

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United States

I'll try more time

Let me tell you that the pdrn infusion for me is working slowly. I can see a little difference on my skin but I’m going to try more time to see is going to help me. Thanks

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Melissa

Verified Buyer

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United States

Waiting for the delivery

I bought 3 kits but I never received them due to lost package. They shipped new ones to me, still waiting to try them

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Eric

Verified Buyer

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United States

Maybe too soon

Only done two treatments so far. Nothing bad to say but nothing good either. I guess I just need to keep going and be patient.

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Valerie

Verified Buyer

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United States

Missing my delivery!

I have not received my order ! Can I get a refund!!!

>> Derm replied:
Thank you for reaching out. We have been trying to contact you since June 27 after DHL notified us of a delivery attempt, but we did not receive a response to our messages. Our email support team will send you another message regarding this concern. Thank you.

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John

Verified Buyer

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United States

Received wrong item

I received the wrong item!! Why? please ship me the correct one

>> Derm replied:
Hi John, we apologize for the incovenience. We already shipped the correct item to you. Thank you for your patience.

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Jessica

Verified Buyer

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United States

Don’t see the hype about it

I have used it for three weeks now and have not noted any difference. Even on the day off I don’t think it is effective at all. The price for the tool is not justifiable. It’s quite disappointing. I’ll continue using it and hopefully I’ll be wrong.

>> Derm replied:
Hi! Thanks for your feedback. We totally get that waiting for results can be tough. According to some researches, skin cell proliferation and collagen remodeling triggered by micro-infusion and PDRN can take up to 3 months. It’s very similar to going to the gym, you don’t see abs after one week, but consistency pays off. Many of our users start noticing changes between the 8th and 12th week. We truly appreciate your patience and commitment, and we're always here if you need support along the way!

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Layla

Verified Buyer

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United States

Nothing until now

I used it for almost one month but nothing yet. I will continue using it for other 1-2 months otherwise I will return it

>> Derm replied:
Hi Layla! Thank you for sharing your honest feedback. While we understand it can be frustrating not to see immediate results, skin regeneration especially with deep wrinkles and sagging takes time. We encourage you to stay consistent with the treatments as most users start seeing more noticeable changes after 8–12 weeks. Our team is here to support you if you have any questions in the meantime!

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Nina

Verified Buyer

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United States

Not working, last chance

I have been using the derm pdrn infusion system along for about 2 months, and have not seen any improvement. Very bummed. My skin looks great the day after the treatment but after the swelling goes down, its back to looking the same. I will give it last chance

>> Derm replied:
Hi Nina, thank you for your feedback. Everyone's skin is different, and we understand that you haven't noticed any difference yet. It's also true that in your case, it's only been two months, and for most people, usually three months are required to see the first results. We are confident that if you are consistent, you will start to see the first results in the third month. If not, you can contact our team at support@try-derm.com for a refund.

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Eddie

Verified Buyer

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United States

Never got the product

Was excited to try it but product was not delivered even after a month and payment was taken immediately. Ridiculous that I’m being asked for feedback

>> Derm replied:
Hi Eddie, upon checking with our team we never received any email from you. That being said, we apologize for what happened and we just sent you a new product totally for free. We will keep you updated about your shipping. Thank you